Compile Data Set for Download or QSAR
Found 850 of ic50 data for polymerid = 6108
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6K81PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50258539((S)-1-methyl-N-(1-(5-(naphthalen-2-yl)-1H-imidazol...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6K81PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6K81PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM162865(US9056843, 156)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8Z98PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504572((S)-5-(Benzo[d]oxazol-2-yl)-4-(4-(5-(trifluorometh...)copy SMILES
Affinity DataIC50: 2nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50424998(CHEMBL2312164)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human HDAC5 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CRKPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504735((R)-4-(2,5- difluoro-4-(5- (trifluoromethyl)- 1,2,...)copy SMILES
Affinity DataIC50: 3nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HH8PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human HDAC5 expressed in baculovirus infected sf9 cells using (Boc-Lys(trifluoroacetyl)-AMC) as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76H9KPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50424996(CHEMBL2312168)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human HDAC5 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D79CRKPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM162846(US9056843, 137)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC14PTPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504543((S)-5-(3-(Pyridin-2-yl)-1,2,4-oxadiazol-5-yl)-1-(4...)copy SMILES
Affinity DataIC50: 5nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8KZJPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length human HDAC5 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3QVSPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant full length human HDAC5 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 3 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26976Z8PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of HDAC5 by in vitro deacetylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3SKDPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504529((S)-1-(2,5-Difluoro-4-(5-(trifluoromethyl)-1,2,4-o...)copy SMILES
Affinity DataIC50: 7nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504874(8-fluoro- 2-({3- fluoro-4-[5- (trifluoro- methyl)-...)copy SMILES
Affinity DataIC50: 7nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81ZSPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human recombinant HDAC5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2NTXPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human recombinant HDAC5 using Boc-Lys(triflouroacetyI)-AMC substrate incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3J6HPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X89Z5PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Tested in vitro for antagonist activity against H3 receptor of guinea pig jejunum.More data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human HDAC5 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PMPPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human recombinant HDAC5 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9CG0PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504824(2-({3- fluoro-4-[5- (trifluoro- methyl)- 1,2,4-oxa...)copy SMILES
Affinity DataIC50: 8.40nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM505065(4-({5-[5- (trifluoro- methyl)- 1,2,4-oxa- diazol-3...)copy SMILES
Affinity DataIC50: 9.60nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM162846(US9056843, 137)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474FHWPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM173621(US9096627, CY190602 )copy SMILEScopy InChI
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9GTQPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504536((S)-1-(2,3-Difluoro-4-(5-(trifluoromethyl)-1,2,4-o...)copy SMILES
Affinity DataIC50: 11nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50307768(7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human HDAC5 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5TGQPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563273(CHEMBL4748500)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human HDAC5 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PMPPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 12.5nMAssay Description:HDAC enzyme inhibition assays were performed using purified HDACs 1-10 essentially as described in Beckers et al., 2007, Int. J. Cancer., 121:1138-48...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B5BUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50563274(CHEMBL4799406)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human HDAC5 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1PMPPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154GX2PubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50503692(CHEMBL4437833)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human C-terminal His-tagged HDAC5 catalytic domain (656 to 1122 residues) expressed in baculovirus infected Sf9 insect cells using Boc-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44TJZPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human HDAC5 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8KZJPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504698(US11066396, Example 124 | tert-butyl (S)-1- (2,3-d...)copy SMILES
Affinity DataIC50: 17nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of human HDAC5 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V989KVPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504677((S)-1-(2,5- difluoro-4-(5- (trifluoromethyl)- 1,2,...)copy SMILES
Affinity DataIC50: 18nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504515((R)-4-(3-Fluoro-4-(5-(trifluoromethyl)-1,2,4-oxadi...)copy SMILES
Affinity DataIC50: 18nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504582(1-(2,5-difluoro-4- (5-(trifluoromethyl)- 1,2,4-oxa...)copy SMILES
Affinity DataIC50: 19nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504542((R)-3-(2,5-Difluoro-4-(5-(trifluoromethyl)-1,2,4-o...)copy SMILES
Affinity DataIC50: 19nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50552915(CHEMBL4798111)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474FHWPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504696((S)-5-(3-methyl- 1,2,4-oxadiazol-5- yl)-1-(4-(5- (...)copy SMILES
Affinity DataIC50: 21nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504828(2-({3- fluoro-4-[5- (trifluoro- methyl)- 1,2,4-oxa...)copy SMILES
Affinity DataIC50: 21nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50304783((+)-2-(4-(4-(4-fluorophenyl)-1-hydroxybut-3-en-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB81ZSPubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM505072(1-({5-[5- (trifluoro- methyl)- 1,2,4-oxa- diazol-3...)copy SMILES
Affinity DataIC50: 22nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504852(2-fluoro- 7-({3- fluoro-4-[5- (trifluoro- methyl)-...)copy SMILES
Affinity DataIC50: 24nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
TargetHistone deacetylase 5(Homo sapiens (Human))
IRBM/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM504580(6-phenyl-1-(4-(5- (trifluoromethyl)- 1,2,4-oxadiaz...)copy SMILES
Affinity DataIC50: 25nMAssay Description:HDAC5 reagents: N-terminal GST tagged HDAC5 was purchased from BPS Bioscience [catalog #50045]. Assays were performed with buffer containing 20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DN485ZUS Patent
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